fosaprepitant will boost the stage or outcome of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.Monitor Carefully (1)mitotane decreases amounts of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Mitotane is a strong inducer of cytochrome P-4503A4; keep an eye on